This hotel’s history dates back to 500 years ago and, from being a monastery, it has now become a prestigious hotel

The Supreme Sacred Congregation of the Roman and Universal Inquisition, also called Sant’Uffizio, was created in 1542 by Pope Paul III who proclaimed the Licet ab initio Apostolic Constitution. It corresponds to the old Inquisition and is named Sacred Congregation for the Doctrine of the Faith.

This ancient house in the heart of Monferrato is surrounded by vineyards and pretty red brick villages, tucked away in the green hills all around. These places evoke sixteenth century atmospheres, when the guesthouse was a monastery and belonged to the Inquisition tribunals, venue of the Dominican Inquisitor of Casale, that depended directly on the Roman Catholic Church.

This is where the Dominicans, who defended the strict rules of the ecclesiastical tribunal, used to grow silkworms and produce a very good wine for Mass. It was so nice in fact, that the Franciscans, who were owners of three convents near Moncalvo, were jealous of them.

Apart from this, its history is similar to that of other properties of the clergy. Dismembered by Napoleon, who conquered Monferrato after the battle of Marengo in which the Austrians were defeated, the property was returned to its legitimate owners and became a farming estate. It was then abandoned again but came back to life in the eighties when it was one of the most highly-rated restaurants in Piedmont, famous for its white truffles and selection of wines, among the best in the region, including Barbera and Barolo.

In September 2012 came the opening of the new SPA AQUANATURA. After taking just over one year to renovate the new SPA, the hotel changed its name from Locanda del Sant'Uffizio to RELAIS SANT'UFFIZIO WELLNESS Hotel & SPA.

The Relais Sant’Uffizio never stopped. The renovation of the historic restaurant of Cioccaro began in June 2014, ending with the opening in May 2015 of an additional dependence with 13 new rooms, meeting room and panoramic terrace - all surrounded by nature.

The newly renovated hotel offers an elegant environment that will strike you through harmony and refinement. Our careful and discreet hospitality will make you feel at home while you enjoy a relaxing vacation in nature.

After an accurate restauration, the seventeenth-century Relais Sant'Uffizio has once again found its ancient shine. All the rooms and suite of the hotel have been elegantly restored, recovering the nineteenth-century frescos, the marian icons and the ancient cells of the monks of the convent.

These 54 extraordinary rooms and suites are elegantly furnished and endowed with all necessary comforts. They include the Garden and Romantik rooms with swimming pool out front, the Junior Suites and classic Suites in the heart of the hotel, plus the Mansards that lean out over the marvellous countryside views surrounding the Relais Sant'Uffizio Wellness Hotel & SPA, this fine wellness hotel in the Langhe and in the Monferrato area.

Many of these characteristics have made this wellness hotel in Piedmont known all over the world. A wellness hotel of charm and luxury in beautiful Piedmont is perfect to spend a vacation or a romantic weekend in comfort and style.



The Sant’Uffizio is always available and active to receive your inquiries and bookings.


RESTAURANT LA LOCANDA del Sant’Uffizio with its fine wines and food, prepared with exquisite detail by our chef Marco Mazzocco. A prestigious restaurant where you can taste the famous white truffle, accompanied by a large selection of prestigious Piemonte wines such as Barbera and Barolo.
Discover LA LOCANDA del Sant’Uffizio today!

WELLNESS AQUANATURA open daily from 10:00am, with a range of hydroptherapy and thermal treatments. SPA entry includes access for external guests who want to enjoy some peace and relaxation. Aquanatura is also a beauty centre where you can book massages and treatments.

Nr. 2 OUTDOOR SWIMMING POOL in the beautiful Italian sunshine, open from May to September for relaxation. Access to the pool is included in the room rate for our guests, and available to external guests for a small entry fee. The LAVIGNA SWIMMING POOL is surrounded by the park and vineyard, located in the heart of the Relais.

GARDENIA LOUNGE BAR AND POOL BAR open to all hotel guests and day SPA visitors. The stunning bars are nestled in the hills surrounding Relais, and are ideal for cocktails, brunch or small parties. You can also have lunch here every day between 12:00pm and 18:00pm.

TENNIS COURT open daily for guests who want to play a few sets among the peaceful local hills and countryside. Access to the tennis court is included in the room rate and also available on request for external guests. Equipment can be requested from the hotel if you wish to play - speak to our helpful staff.

These and many other services are offered at the Sant’Uffizio. MOUNTAIN BIKES are available to borrow, so you can check out the lovely local countryside. Visit the Limonaia, where guests can start the day with a nice breakfast of local produce, see the Teatro del Vino wine cellar, with more than 300 bottles and stroll in the manicured Italian Garden of the 17th century.

The Sant’Uffizio is the ideal place to rejuvenate and rediscover peace, the silence of nature and the scent of the vineyards. Relax in the enchanting Aquanatura SPA, and enjoy the restaurant La Locanda Del Sant'Uffizio’s dishes and wines which make this corner of paradise famous worldwide.

Contact us to arrange your visit!